Fixing Two-Nucleon Weak-Axial Coupling L_{1,A} From mu-d Capture

We calculate the muon capture rate on the deuteron to next-to-next-to-leading order in the pionless effective field theory. The result can be used to constrain the two-nucleon isovector axial coupling L_{1,A} to +/- 2 fm^3 if the muon capture rate is measured to 2% level. From this, one can determine the neutrino-deuteron break up reactions and the pp-fusion cross section in the sun to a same level of accuracy.Comment: replaced by the version appearing in the PR

Effect of Obstructive Jaundice and Nitric Oxide on the Profiles of Intestinal Bacterial Flora in Wild and iNOS−/− Mice

We previously reported that the plasma level of endotoxin and colonic expression of IgA in the mouse increased with obstructive jaundice induced by bile duct ligation (BDL). To elucidate the mechanism of the BDL-induced increase, we analyzed the effect of BDL on intestinal flora in wild type and inducible nitric oxide synthase (iNOS)-deficient mice (iNOS−/−) using the terminal restriction fragment length polymorphism analysis (T-RFLP) and 16S rDNA clone libraries. The amounts of bacterial DNA detected in fecal samples from both animal groups pretreated with antibiotics were extremely low as compared with untreated groups. We found that the profiles of enteric bacteria changed markedly after BDL. The bacterial composition is significantly different between not only wild type and iNOS−/− mice but also those before and after BDL, respectively. Among enteric bacteria examined, Lactobacillus murinus was found to increase markedly after BDL in rectum of both animal groups. However, Escherichia coli markedly increased after BDL in the iNOS−/− mice. These findings suggest that profiles of enteric flora change markedly in animals during obstructive jaundice by some mechanism that is affected by bile constituents and iNOS-derived NO

In vitro assembly of xenotropic murine leukemia virus-related virus CA-NC protein

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Language relativity in legacy literature : a systematic review in multiple languages

Since the Olympic Agenda 2020, legacy has been widely used as a justification for hosting the Olympic Games, through which sustainable development can be achieved for both events and host cities. To date, no universal definition of legacy has been established, which presents challenges for legacy-related international knowledge transfer among host cities. To address this gap, a multilingual systematic review of the literature regarding the concept of legacy was conducted in French, Japanese, Chinese, and English. Using English literature as a baseline, points of convergence and divergence among the languages were identified. While all four languages value the concept of legacy as an important facet of mega-events, significant differences were found within each language. This finding highlights the importance of strategies that align different cultures when promoting sustainable development of some global movements such as the Olympic legacy. Sport management is replete with international topics, such as international events and sport for development, and each topic is studied simultaneously in several languages and with potentially differing frameworks and perspectives. Thus, literature reviews that examine the English literature, exclusively, are innately limited in scope. The development of partnerships and resources that facilitate cross-lingual and cross-cultural consultation and collaboration is an important research agenda. More research is needed on knowledge translation across languages

Drivers of the perceived social impact of the Super Bowl: mediation and moderation analyses

Purpose: Building on the social leverage model (SLM), this study aims to examine the influence of event-related attributes on residents' perceived social impact of a major sport event, as mediated by event involvement. It also investigates the moderating effect of event rights holders' credibility on the relationship between event involvement and perceived social impact. Design/methodology/approach: Using a two-wave, time-lagged survey, data were collected from 220 residents of a Super Bowl host city. Hypotheses were tested using structural equation modeling (SEM). Findings: High celebratory atmosphere, social camaraderie and social responsibility as perceived before the event were associated with residents' perceptions of the social impact of the Super Bowl. Moreover, the association between social camaraderie and perceived social impact was mediated by event involvement. When appraising the rights holder as credible, involved residents reported an increased level of perceived social impact. Originality/value: This study contributes to research on the SLM by demonstrating its application among indirect participants of major sport events. Additionally, it suggests the imperative role of rights holders' credibility in promoting the perceived social impact among involved residents

Bis[μ-2-(2,4-difluoro­phen­yl)-1,3-bis­(1,2,4-triazol-1-yl)propan-2-olato-κ4 N 2,O:O,N 2′]bis­[(acetato-κ2 O,O′)nickel(II)] methanol hemisolvate

In the title complex, [Ni2(C13H11F2N6O)2(C2H3O2)2]·0.5CH3OH, there are two half-molecules in the asymmetric unit. The two centrosymmetrically related NiII atoms, each attached to an acetate ligand, are linked by two fluconazole ligands. Each NiII atom is six-coordinated in a distorted octa­hedral geometry by two N atoms of the triazole groups and two bridging O atoms from two different fluconazole ligands and two O atoms from a chelating acetate ligand. In the crystal structure, the half-occupied methanol solvent mol­ecule is linked to a triazole group via an O—H⋯N hydrogen bond

Neuron–astrocyte signaling network in spinal cord dorsal horn mediates painful neuropathy of type 2 diabetes

Activation of the neuronal–glial network in the spinal cord dorsal horn (SCDH) mediates various chronic painful conditions. We studied spinal neuronal–astrocyte signaling interactions involved in the maintenance of painful diabetic neuropathy (PDN) in type 2 diabetes. We used the db/db mouse, an animal model for PDN of type 2 diabetes, which develops mechanical allodynia from 6 to 12 wk of age. In this study, enhanced substance P expression was detected in the presynaptic sensory fibers innervating lamina I–III in the lumbar SCDH (LSCDH) of the db/db mouse at 10 wk of age. This phenomenon is associated with enhanced spinal ERK1/2 phosphorylation in projection sensory neurons and regional astrocyte activation. In addition, peak phosphorylation of the NR1 subunit of N ‐methyl‐ D ‐aspartate receptor (NMDAR), along with upregulation of neuronal and inducible nitric oxide synthase (nNOS and iNOS) expression were detected in diabetic mice. Expression of nNOS and iNOS was detected in both interneurons and astrocytes in lamina I–III of the LSCDH. Treatment with MK801, an NMDAR inhibitor, inhibited mechanical allodynia, ERK1/2 phosphorylation, and nNOS and iNOS upregulation in diabetic mice. MK801 also reduced astrocytosis and glial acidic fibrillary protein upregulation in db/db mice. In addition, N(G)‐nitro‐L‐arginine methyl ester (L‐NAME), a nonspecific NOS inhibitor, had similar effects on NMDAR signaling and NOS expression. These results suggest that nitric oxide from surrounding interneurons and astrocytes interacts with NMDAR‐dependent signaling in the projection neurons of the SCDH during the maintenance of PDN. © 2012 Wiley Periodicals, Inc.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/92403/1/22349_ftp.pd